Mumakore achangopfuura, dambudziko rekufutisa pasi rose rave rakanyanya kuipa. Sekureva kwe "Global Obesity Atlas 2025" yakaburitswa neWorld Obesity Federation, huwandu hwevanhu vakuru vakafutisa pasi rose hunotarisirwa kuwedzera kubva pamamiriyoni 524 muna 2010 kusvika mabhiriyoni 1.13 muna 2030, kuwedzera kweanopfuura 115%. Zvichienderana neizvi, nhamba iri kuwedzera yevatengi vari kutsvaga zvinhu zvechisikigo zvinogona kubatsira kudzivirira kufutisa. Muna Chikumi gore rino, chidzidzo chakaburitswa mujenari rekuti "npj science of food" chakaratidza kuti curcumin inoderedza kuunganidzwa kwemafuta emukati membeva dzeMASH nekudzivirira kuburitswa kwegastric inhibitory polypeptides (GIP) inokonzerwa nekukuvara kwemudumbu kusingapinze. Kuwanikwa uku hakungopi mazano matsva ekudzivirira kufutisa asiwo kunowedzera musika wekushandisa curcumin.
Curcumin inodzivirira sei kuunganidzwa kwemafuta emuviri? Kuunganidzwa kwemafuta emuviri zvinoreva kuunganidzwa kwemafuta kusingawanzoitiki kana kwakawandisa. Kudya kwakawanda kwemakabhohaidhiretsi, mafuta akawanda uye kusaita maekisesaizi zvinogona kukonzera kusawirirana kwesimba, zvichikonzera mafuta emuviri akawandisa. Nzira yekugaya chikafu inzvimbo yakakosha yekunwa mafuta. Kuunganidzwa kwemafuta emuviri chinhu chakakosha che steatohepatitis (MASH) inokonzerwa nekutadza kushanda zvakanaka kwemuviri. Sekureva kwetsvagurudzo, curcumin nemishonga inorwisa mabhakitiriya inogona kuderedza huremu hwemuviri wemakonzo eMASH, uye curcumin nemishonga inorwisa mabhakitiriya ine simba rekubatsirana.
Ongororo yezvekuita yakawana kuti curcumin inonyanya kuderedza huremu hwemafuta emukati memuviri, kunyanya munyama dzemudumbu. Curcumin inodzivirira kuwedzera kwehuremu nekudzvinyirira kuburitswa kweGIP uye kuderedza index yemafuta akakomberedza itsvo. Kuderedzwa kwekuburitswa kweGIP mudumbu kunokonzerwa neCurcumin kunodzivirira kushanda kweGIP receptors, nokudaro kuderedza adipogenesis nekuzvimba munyama dzemafuta emudumbu. Pamusoro pezvo, curcumin inogona kuderedza hypoxia yemudumbu mudiki nekudzivirira epithelium yemudumbu nemutsinga weropa, nokudaro ichideredza kuburitswa kweGIP. Mukupedzisa, mhedzisiro ye curcumin pamafuta emukati memuviri inonyanya kuderedza kuburitswa kweGIP nekudzivirira hypoxia inokonzerwa nekukanganiswa kwemudziyo wemudumbu.
Curcumin, "nyanzvi yekudzivirira kuzvimba", inonyanya kubva kumidzi nema rhizomes eCurcuma (Curcuma longa L.). Imusanganiswa wepolyphenolic une uremu hushoma uye unowanzo shandiswa semusanganiswa muzvikafu zvakasiyana-siyana. Muna 1815, Vegel nevamwe vake vakatanga kutaura nezvekubviswa kwe "chinhu cheorenji-yero" kubva ku rhizome ye turmeric ndokuchitumidza kuti curcumin. Zvakatoitika muna 1910 apo Kazimierz nevamwe masayendisiti vakaona chimiro chayo chemakemikari se diferulic acylmethane. Humbowo huripo hunoratidza kuti curcumin ine simba guru rekudzivirira kuzvimba. Inogona kushandisa simba rayo rekudzivirira kuzvimba nekudzivisa Toll-like receptor 4 (TLR4) pathway uye nzira yayo yekuratidza nuclear factor kB (NF-kB), uye kuderedza kugadzirwa kwezvinhu zvinodzivirira kuzvimba zvakaita se interleukin-1 β(IL-1β) uye tumor necrosis factor -α(TNF-α). Panguva iyi, hunhu hwayo hwekudzivirira kuzvimba hunoonekwa sehwaro hwemabasa akasiyana-siyana ehupenyu, uye huwandu hwakawanda hwezvidzidzo zvepamberi pekiriniki kana zvekiriniki zvakaongorora kushanda kwayo muzvirwere zvekuzvimba. Pakati pazvo, chirwere chemudumbu chinozvimba, arthritis, psoriasis, kuora mwoyo, atherosclerosis uye COVID-19 ndidzo nzvimbo dzinotsvakurudzwa zvakanyanya pari zvino.
Nekukura kwemusika wemazuva ano, curcumin yakaoma kusvika padanho rinoshanda kuburikidza nekudya chete uye inoda kutorwa muchimiro chezvinowedzera. Nokudaro, yakakura zvakanyanya muminda yechikafu chine hutano uye zvinowedzera zvekudya.
Justgood Health yakagadzirawo mhando dzakasiyana dzema supplements e curcumin gummy nema capsules e curcumin. Vatengesi vazhinji vauya kuzogadzirisa huwandu hwemushonga kana chimiro chemhando yavo.
Tsvakurudzo yakawanda pamusoro pemabhenefiti e curcumin yakawana kuti curcumin haingobatsiri chete kurwisa kufuta asiwo ine mhedzisiro yakawanda senge antioxidation, neuroprotection, relieve pain of bones and support for cardiovascular health. Antioxidant: Tsvakurudzo yakawana kuti curcumin inogona kubvisa zvakananga ma free radicals uye kuvandudza mashandiro e mitochondrial nekuita kuti nzira dzakadai sekunyaradza regulatory protein 3 (SIRT3), nokudaro ichideredza kugadzirwa kwe excessive reactive oxygen species (ROS) kubva kunobva uye zvinobudirira kuderedza kukuvara kwemasero. Neuroprotection: Humbowo hwetsvagurudzo huripo hunoratidza kuti kuzvimba kwakabatana zvakanyanya nekuora mwoyo. Curcumin inogona kuvandudza zviratidzo zvekuora mwoyo uye kunetseka zvevarwere vane kuora mwoyo. Curcumin inogona kubatsira kudzivirira kukuvara kwe neuronal kunokonzerwa ne interleukin-1 β (IL-1β) nezvimwe zvinhu, uye kuderedza maitiro akafanana nekuora mwoyo anokonzerwa nekushushikana kusingaperi. Nokudaro, inogona kutamba basa rakanaka mukutsigira hutano hwehuropi uye kudzora manzwiro. Kuderedza marwadzo e musculoskeletal: Zvidzidzo zvakaratidza kuti curcumin inogona kuvandudza zviratidzo zvekiriniki zvemhuka dze arthritis uye kudzivirira majoini netsandanyama nekuderedza kuzvimba. Curcumin inogona kuderedza marwadzo emapfupa nemapfupa nekuti inogona kudzivirira zvakanyanya kuburitswa kwezvinhu zvinokonzera kuzvimba zvakaita se tumor necrosis factor -α(TNF-α) uye interleukin-1 β(IL-1β), kuderedza kuzvimba kwemunzvimbo, uye nekudaro kuderedza zviratidzo zvekuzvimba nekurwadziwa kwemajoini. Kutsigira hutano hwemwoyo: Panyaya yemwoyo, curcumin inogona kushanda nekudzora mafuta eropa, kuderedza cholesterol yeserum, triglycerides uye low-density lipoprotein cholesterol levels, ukuwo ichiwedzera high-density lipoprotein cholesterol levels. Pamusoro pezvo, curcumin inogonawo kudzivirira kuwanda kwemasero emhasuru akapfava uye kuzvimba, izvo zvinobatsira mukudzivirira kuitika uye kukura kwezvirwere zvemwoyo zvakaita se atherosclerosis.
Nguva yekutumira: Ndira-08-2026