Astaxanthin (3,3'-dihydroxy-beta, beta-carotene-4,4'-dione) i carotenoid, inowanikwa mumhando dzakasiyana-siyana dzemabhakitiriya nemhuka dzemugungwa, uye pakutanga yakaparadzaniswa nemarobster naKuhn naSorensen. Ipigment inonyunguduka mafuta inoita seorenji kusvika kutsvuku uye haina vhitamini A inobatsira mumuviri wemunhu.
Zvinhu zvakasikwa zvinopa astaxanthin zvinosanganisira algae, yeast, salmon, trout, krill ne crayfish. Astaxanthin yekutengeserana inonyanya kuwanikwa kubva kuFife yeast, red algae uye chemical synthesis. Imwe yenzvimbo dzakanakisisa dzinopa astaxanthin yechisikigo ired chlorella inonaya mvura, ine astaxanthin inosvika 3.8% (nehuremu hwakaoma), uye wild salmon zvakare inzvimbo dzakanaka dzinopa astaxanthin. Kugadzirwa kwechisikigo kuchiri iko kunobva astaxanthin nekuda kwemutengo wakakwira wekurima Rhodococcus rainieri. Basa rehupenyu reastaxanthin inogadzirwa nemakemikari i50% chete yeastaxanthin yechisikigo.
Astaxanthin inowanikwa se stereoisomers, geometric isomers, ma free uye esterified forms, ine stereoisomers (3S,3'S) uye (3R,3'R) ndiyo yakawanda kwazvo. Rhodococcus rainieri inogadzira (3S,3'S)-isomer uye mbiriso yeFife inogadzira (3R,3'R)-isomer.
Astaxanthin, chinhu chinopisa chenguva ino
Astaxanthin ndiyo chinhu chinonyanya kukosha muzvikafu zvinoshanda muJapan. Nhamba dzeFTA pamusoro pekuzivisa kwechikafu chinoshanda muJapan muna 2022 dzakaona kuti astaxanthin yaive panhamba 7 pakati pezvinhu gumi zvepamusoro maererano nekushandiswa kwaiitwa kakawanda, uye yainyanya kushandiswa muminda yehutano hwekuchengetedza ganda, kuchengetedza maziso, kuderedza kuneta, uye kuvandudza mashandiro epfungwa.
PaMubairo weZvinhu Zvinovaka Muviri zveAsia wa2022 na2023,Hutano hweJustgood Chinhu che astaxanthin chechisikigo chakazivikanwa sechinhu chakanakisa chegore kwemakore maviri akateedzana, chinhu chakanakisa mu cognitive function track muna 2022, uye chinhu chakanakisa mu oral beauty track muna 2023. Pamusoro pezvo, chinhu ichi chakaiswa muAsian Nutritional Ingredients Awards - Healthy Aging track muna 2024.
Mumakore achangopfuura, tsvakiridzo yezvedzidzo pamusoro peastaxanthin yatangawo kuwedzera. Sekureva kwedata rePubMed, pakutanga kwa1948, kwakaitwa zvidzidzo pamusoro peastaxanthin, asi kutarisisa kwave kwakaderera, kutanga muna 2011, zvikoro zvakatanga kutarisa paastaxanthin, nemabhuku anodarika zana pagore, uye anopfuura mazana maviri muna 2017, anopfuura mazana matatu muna 2020, uye anopfuura mazana mana muna 2021.
Chitubu chemufananidzo: PubMed
Panyaya yemusika, zvichienderana neFuture market insights, musika wepasi rose weastaxanthin unofungidzirwa kuva USD 273.2 miriyoni muna 2024 uye unotarisirwa kusvika USD 665.0 miriyoni panosvika 2034, paCAGR ye9.3% panguva yekufanotaura (2024-2034).
Kukwanisa kwakanyanya kwe antioxidant
Maumbirwo akasiyana eAstaxanthin anoita kuti ive nehutachiona hwakanyanya. Astaxanthin ine ma bond maviri akasanganiswa, hydroxyl neketone groups, uye inopfachukira uye inopfachukira. Ma bond maviri akasanganiswa ari pakati pekombuta anopa maerekitironi uye anoita ma free radicals kuti aashandurwe kuita zvigadzirwa zvakagadzikana uye kugumisa free radical chain reactions muzvisikwa zvakasiyana-siyana. Basa rayo rehupenyu rakapfuura remamwe ma antioxidants nekuda kwekugona kwayo kubatana nemasero kubva mukati zvichienda kunze.
Nzvimbo yeastaxanthin nedzimwe antioxidants mumasero
Astaxanthin inoita basa guru rekudzivirira ma "antioxidant" kwete chete kuburikidza nekubvisa ma "free radicals" zvakananga, asiwo kuburikidza nekushanda kwe "cellular antioxidant defense system" nekutonga nzira ye "nuclear factor erythroid 2-related factor (Nrf2). Astaxanthin inodzivirira kuumbwa kweROS uye inodzora kuratidzwa kwema "oxidative stress-responsive enzymes", akadai seheme oxygenase-1 (HO-1), inova chiratidzo chekushushikana kwe "oxidative stress".HO-1 inodzorwa nezvinhu zvakasiyana-siyana zvinonzwa kushushikana, kusanganisira Nrf2, iyo inobatanidza kune zvinhu zvinopindura ma "antioxidant" munzvimbo inokurudzira detoxification metabolism enzymes.
Rudzi rwakazara rwemabhenefiti eastaxanthin uye mashandisirwo ayo
1) Kuvandudzwa kwebasa rekuziva
Ongororo dzakawanda dzakaratidza kuti astaxanthin inogona kunonotsa kana kuvandudza kusashanda zvakanaka kwepfungwa kunokonzerwa nekukwegura kwakajairika kana kuderedza pathophysiology yezvirwere zvakasiyana-siyana zvinokanganisa tsinga. Astaxanthin inogona kuyambuka chipingamupinyi cheropa-uropi, uye zvidzidzo zvakaratidza kuti astaxanthin yekudya inoungana mu hippocampus ne cerebral cortex yeuropi hwemakonzo mushure mekudya kamwe chete uye kakawanda, izvo zvinogona kukanganisa kuchengetedza nekuvandudza mashandiro epfungwa. Astaxanthin inokurudzira kugadzurwa kwemasero etsinga uye inowedzera kuratidzwa kwemajini e glial fibrillary acidic protein (GFAP), microtubule-associated protein 2 (MAP-2), brain-derived neurotrophic factor (BDNF), uye growth-associated protein 43 (GAP-43), mapuroteni ane chekuita nekupora kweuropi.
Makapusule eJustgood Health Astaxanthin, ane Cytisine neAstaxanthin kubva kuRed Algae Rainforest, anoshanda pamwe chete kuti awedzere kushanda kwehuropi.
2) Dziviriro yeMaziso
Astaxanthin ine basa rekudzivirira maziso rinoita kuti mamorekuru asina oxygen ashande zvakanaka uye rinodzivirira maziso. Astaxanthin inoshanda pamwe chete nemamwe macarotenoids anotsigira hutano hwemaziso, kunyanya lutein nezeaxanthin. Pamusoro pezvo, astaxanthin inowedzera mwero wekuyerera kweropa muziso, zvichibvumira ropa kuti riwedzere mweya mu retina nemaziso. Zvidzidzo zvakaratidza kuti astaxanthin, pamwe chete nemamwe macarotenoids, inodzivirira maziso kubva mukukuvadzwa muzuva rose. Pamusoro pezvo, astaxanthin inobatsira kuderedza kusagadzikana kwemaziso uye kuneta kwekuona.
Zvishandiso zveJustgood Health Blue Light Protection Softgels, Zvishandiso zvikuru: lutein, zeaxanthin, astaxanthin.
3) Kuchengetedza Ganda
Kushushikana kweganda (oxidative stress) chinhu chikuru chinokonzera kukwegura kweganda revanhu uye kukuvara kweganda. Maitiro ekukwegura kwemukati (kwenguva) uye kwekunze (kwechiedza) kugadzirwa kweROS, mukati memuviri kuburikidza neoxidative metabolism, uye kunze kuburikidza nekuratidzwa kuzuva nemwaranzi ye ultraviolet (UV). Zviitiko zvekukwegura kweganda zvinosanganisira kukuvara kweDNA, kuzvimba, kudzikira kwe antioxidants, uye kugadzirwa kwe matrix metalloproteinases (MMPs) zvinokanganisa collagen ne elastin mudermis.
Astaxanthin inogona kudzivirira zvinobudirira kukuvara kwe oxidative kunokonzerwa ne free radicals uye kupinza kweMMP-1 muganda mushure mekusvikwa neUV. Zvidzidzo zvakaratidza kuti astaxanthin kubva kuErythrocystis rainbowensis inogona kuwedzera huwandu hwe collagen nekudzivirira kuburitswa kweMMP-1 neMMP-3 mu dermal fibroblasts yemunhu. Pamusoro pezvo, astaxanthin yakaderedza kukuvara kweDNA kunokonzerwa neUV uye yakawedzera kugadziriswa kweDNA mumasero akasvikwa nemwaranzi yeUV.
Justgood Health parizvino iri kuita zvidzidzo zvakati wandei, zvinosanganisira makonzo asina vhudzi uye miedzo yevanhu, iyo yese yakaratidza kuti astaxanthin inoderedza kukuvara kweUV kune zvikamu zvakadzika zveganda, izvo zvinokonzera kuoneka kwezviratidzo zvekukwegura kweganda, zvakaita sekuoma, ganda rinorembera uye makwinya.
4) Kudya kwemitambo
Astaxanthin inogona kukurumidzisa kugadziriswa mushure mekurovedza muviri. Kana vanhu vachirovedza muviri kana kurovedza muviri, muviri unogadzira huwandu hwakawanda hweROS, iyo, kana ikasabviswa nenguva, inogona kukuvadza tsandanyama uye kukanganisa kupora kwemuviri, nepo basa rakasimba re astaxanthin rekudzivirira muviri richigona kubvisa ROS nenguva uye kugadzirisa tsandanyama dzakakuvara nekukurumidza.
Justgood Health inoburitsa Astaxanthin Complex yayo itsva, musanganiswa wemagnesium glycerophosphate, vhitamini B6 (pyridoxine), uye astaxanthin inoderedza marwadzo emhasuru nekuneta mushure mekurovedza muviri. Fomura iyi yakavakirwa paJustgood Health's Whole Algae Complex, iyo inopa astaxanthin yechisikigo isingangodziviriri tsandanyama kubva mukukuvadzwa kwe oxidative chete, asiwo inowedzera kushanda kwetsandanyama uye inovandudza kushanda kwemitambo.
5) Hutano hweMwoyo neMitsipa yeMwoyo
Kushushikana kweropa uye kuzvimba ndizvo zvinonyanya kukonzera chirwere chemwoyo chinonzi atherosclerotic cardiovascular disease. Basa guru re astaxanthin rekudzivirira muviri rinogona kudzivirira nekuvandudza atherosclerosis.
Justgood Health Triple Strength Natural Astaxanthin Softgels dzinobatsira kuchengetedza hutano hwemwoyo nekushandisa astaxanthin yechisikigo inobva murainbow red algae, zvinhu zvikuru zvinosanganisira astaxanthin, organic virgin coconut oil uye natural tocopherols.
6) Kudzora Dziviriro Yemuviri
Masero emuviri anonzwa zvakanyanya kukuvara kwefree radicals. Astaxanthin inodzivirira dziviriro yemuviri nekudzivirira kukuvara kwefree radicals. Ongororo yakawana kuti astaxanthin mumasero evanhu inogadzira ma immunoglobulins, mumuviri wemunhu astaxanthin supplementation kwemavhiki masere, huwandu hweastaxanthin muropa hwakawedzera, T cells neB cells hwakawedzera, kukuvara kweDNA kwakadzikira, C-reactive protein yakadzikira zvakanyanya.
MaAstaxanthin softgels, astaxanthin isina kugadzirwa, anoshandisa chiedza chezuva, mvura yakaseferwa nelava uye simba rezuva kugadzira astaxanthin yakachena uye ine hutano, iyo inogona kubatsira kusimudzira dziviriro yemuviri, kuchengetedza kuona uye hutano hwemajoini.
7) Kuderedza Kuneta
Ongororo yemavhiki mana yakaitwa nenzira isina kurongeka, isina kupofumadzwa kaviri, inodzorwa ne placebo, yakawana kuti astaxanthin yakabatsira kupora kubva mukuneta kwepfungwa kunokonzerwa nekuona (VDT), zvichideredza huwandu hwakakwira hwe phosphatidylcholine hydroperoxide (PCOOH) muropa panguva yekurovedza muviri kwepfungwa nemuviri. Chikonzero chingave chiri che antioxidant activity uye nzira yekudzivirira kuzvimba ye astaxanthin.
8) Kudzivirira chiropa
Astaxanthin ine mhedzisiro yekudzivirira uye inovandudza matambudziko ehutano akadai se fibrosis yechiropa, kukuvara kwechiropa-ischemia, uye NAFLD. Astaxanthin inogona kudzora nzira dzakasiyana-siyana dzekutumira zviratidzo, dzakadai sekuderedza mashandiro eJNK neERK-1 kuvandudza kuramba insulin muchiropa, kudzivirira PPAR-γ kubudisa mafuta muchiropa, uye kuderedza TGF-β1/Smad3 kubudisa kudzivirira kushanda kweHSCs uye fibrosis yechiropa.
Mamiriro emitemo munyika imwe neimwe
MuChina,astaxanthin kubva kunobva algae tsvuku yemurarabungu inogona kushandiswa sechinhu chitsva chekudya muzvikafu zvechivanhu (kunze kwechikafu chevana), pamusoro pezvo, United States, Canada neJapan zvinobvumirawo astaxanthin kushandiswa muzvikafu.
Nguva yekutumira: Zvita-05-2024