Astaxanthin (3,3'-dihydroxy-beta,beta-carotene-4,4'-dione) is carotenoid, yakarongedzerwa selutein, inowanikwa mumhando dzakasiyana siyana dzezvipembenene nemhuka dzemugungwa, uye pakutanga yakaparadzaniswa nemalobster naKuhn naSorensen. I-fat-soluble pigment inoita kunge orenji kusvika kune yakatsvuka muruvara uye haina vhitamini A pro-activity mumuviri wemunhu.
Zvisikwa zviwanikwa zveastaxanthin zvinosanganisira algae, mbiriso, salmon, trout, krill uye crayfish. Commerce astaxanthin inonyanya kutorwa kubva kuFife mbiriso, red algae uye makemikari synthesis. Imwe yeakanakisa masosi echisikigo astaxanthin inonaya tsvuku chlorella, ine astaxanthin yemukati inosvika 3.8% (nehuremu hwakaoma), uye salmon yemusango zvakare masosi akanaka eastaxanthin. Kugadzirwa kweSynthetic kuchiri kunonyanya kukonzera astaxanthin nekuda kwemutengo wakakura wekurima kwakakura kweRhodococcus rainieri. Iyo biological chiitiko cheyakagadzirwa astaxanthin chingori makumi mashanu muzana eiyo yeakasikwa astaxanthin.
Astaxanthin iripo se stereoisomers, geometric isomers, emahara uye esterified mafomu, ane stereoisomers (3S,3'S) uye (3R,3'R) ari iwo akanyanya kuwanda muzvisikwa. Rhodococcus rainieri inogadzira (3S,3'S)-isomer uye Fife yeast inogadzira (3R,3'R) -isomer.
Astaxanthin, kupisa kwechinguva
Astaxanthin ndiyo nyeredzi muzvokudya zvinoshanda muJapan.Nhamba dzeFTA pamusoro pezviziviso zvezvokudya zvinoshanda muJapan muna 2022 yakawana kuti astaxanthin yakaiswa nhamba 7 pakati pezvikamu zvepamusoro zve 10 maererano nehuwandu hwekushandiswa, uye yainyanya kushandiswa muhutano hwehutano hwekuchengetedza ganda, kutarisa kwemaziso, kuneta, uye kuvandudzwa kwekuziva.
Pa2022 uye 2023 Asia Nutritional Ingredients Awards,Justgood Health's natural astaxanthin ingredient yakaonekwa sechinhu chakanakisa chegore kwemakore maviri akateedzana, chinhu chakanakisa mucognitive function track muna 2022, uye chinhu chakanakisa mumuromo werunako runako muna 2023. Pamusoro pezvo, chinhu chacho chakasarudzwa muAsian Nutritional Ingredients 4 track - Health2y Aging02 Awards.
Mumakore achangopfuura, kutsvagisa kwedzidzo paastaxanthin kwatangawo kupisa. Sekureva kwePubMed data, kutanga muna 1948, kwaive nezvidzidzo zveastaxanthin, asi kutarisisa kwave kushoma, kutanga muna 2011, academia akatanga kutarisa astaxanthin, aine zvinopfuura zana zvakadhindwa pagore, uye anopfuura mazana maviri muna 200, anopfuura mazana matatu muna 2020, uye anopfuura mazana maviri muna 2020.
Kwakabva mufananidzo: PubMed
Panyaya yemusika, maererano neRamangwana musika ruzivo, iyo yepasi rose astaxanthin musika saizi inofungidzirwa kuve USD 273.2 miriyoni muna 2024 uye inofungidzirwa kusvika $ 665.0 miriyoni ne2034, paCAGR ye9.3% panguva yekufanotaura (2024-2034).
Superior antioxidant kugona
Astaxanthin yakasarudzika dhizaini inopa iyo yakanyanya kunaka antioxidant kugona. Astaxanthin ine conjugated mbiri zvisungo, hydroxyl uye ketone mapoka, uye ari maviri lipophilic uye hydrophilic. Iyo conjugated kaviri bond pakati pekomboni inopa maerekitironi uye inopindirana nemahara radicals kuti ashandure kuita zvigadzirwa zvakagadzikana uye kumisa mahara radical cheni maitiro mune dzakasiyana siyana. Chiitiko chayo chebiological chepamusoro kune chemamwe antioxidants nekuda kwekugona kwayo kubatanidza kune cell membranes kubva mukati kunze.
Nzvimbo yeastaxanthin uye mamwe ma antioxidants mune cell membranes
Astaxanthin inoshandisa yakakosha antioxidant chiitiko kwete chete kuburikidza nekutsvaira kwakananga kwemahara radicals, asiwo kuburikidza ne activation ye cellular antioxidant defense system nekugadzirisa nyukireya factor erythroid 2-inoenderana chinhu (Nrf2) nzira. Astaxanthin inhibits kuumbwa kweROS uye inogadzirisa kutaura kweiyo oxidative stress-responsive enzymes, yakadai seheme oxygenase-1 (HO-1), iyo inoratidzira ye oxidative stress.HO-1 inogadziriswa nemhando dzakasiyana-siyana dzekushungurudzika-sensitive transcription factors, kusanganisira Nrf2, iyo inosungirirana kune antioxidant-responsive elements in the antioxidant-responsive elements in the antioxidant-responsive elements.
Iyo yakazara yakazara astaxanthin mabhenefiti uye mashandisiro
1) Kuvandudzwa kwebasa rekuziva
Ongororo dzakawanda dzakasimbisa kuti astaxanthin inogona kunonoka kana kuvandudza kushomeka kwekuziva kwakabatana nekuchembera kwakajairika kana kudzikisira pathophysiology yezvirwere zvakasiyana neurodegenerative. Astaxanthin inogona kuyambuka chipingamupinyi cheropa-uropi, uye zvidzidzo zvakaratidza kuti chikafu astaxanthin chinoungana muhippocampus uye cerebral cortex yehuropi hwegonzo mushure mekutora kamwe uye kudzokororwa, izvo zvinogona kukanganisa kuchengetedza nekuvandudza kwekuziva basa. Astaxanthin inokurudzira nerve cell regeneration uye inowedzera gene expression ye glial fibrillary acidic protein (GFAP), microtubule-associated protein 2 (MAP-2), brain-derived neurotrophic factor (BDNF), uye kukura-inosanganiswa neprotein 43 (GAP-43), mapuroteni anobatanidzwa mukupora kwehuropi.
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2) Kudzivirirwa kweziso
Astaxanthin ine antioxidant chiitiko chinomisa okisijeni yemahara radical mamorekuru uye inopa dziviriro yemeso. Astaxanthin inoshanda synergistically nemamwe macarotenoids anotsigira hutano hwemaziso, kunyanya lutein uye zeaxanthin. Uye zvakare, astaxanthin inowedzera mwero wekuyerera kweropa kuziso, ichibvumira ropa kuti riite reoxygenate iyo retina uye yeziso tishu. Zvidzidzo zvakaratidza kuti astaxanthin, pamwe chete nemamwe macarotenoids, inodzivirira maziso kubva mukukuvadzwa kwese kwezuva. Mukuwedzera, astaxanthin inobatsira kubvisa kusagadzikana kwemaziso uye kuneta kwekuona.
Justgood Health Blue Light Dziviriro Softgels, Key ingredients: lutein, zeaxanthin, astaxanthin.
3) Kuchengetedza Ganda
Oxidative kusagadzikana chinhu chakakosha chinokonzeresa kuchembera kweganda remunhu uye kukuvara kwedermal. The mechanism of both intrinsic (chronological) and extrinsic (light) kuchembera ndiko kugadzirwa kweROS, intrinsically through oxidative metabolism, uye extrinsically kuburikidza nekuratidzwa kwezuva ultraviolet (UV) mwaranzi. Zviitiko zveoxidative mukuchembera kweganda zvinosanganisira kukuvara kweDNA, mhinduro dzekuzvimba, kudzikiswa kwea antioxidants, uye kugadzirwa kwematrix metalloproteinases (MMPs) inosvibisa collagen uye elastin mudermis.
Astaxanthin inogona kunyatso kuvharidzira mahara radical-induced oxidative kukuvadzwa uye kuiswa kweMMP-1 muganda mushure mekuratidzwa kweUV. Zvidzidzo zvakaratidza kuti astaxanthin kubva kuErythrocystis rainbowensis inogona kuwedzera collagen yemukati nekudzivisa kutaura kweMMP-1 uye MMP-3 mumunhu dermal fibroblasts. Uye zvakare, astaxanthin yakaderedza UV-induced DNA kukuvadzwa uye yakawedzera DNA kugadzirisa mumasero akafumurwa ne UV mwaranzi.
Justgood Health parizvino iri kuita zvidzidzo zvakati wandei, zvinosanganisira makonzo asina vhudzi uye miedzo yevanhu, izvo zvese zvakaratidza kuti astaxanthin inoderedza kukuvadzwa kweUV kune yakadzika ganda reganda, izvo zvinokonzeresa kutaridzika kwezviratidzo zvekuchembera kweganda, sekuoma, ganda rinodonha uye makwinya.
4) Zvokudya zvemitambo
Astaxanthin inogona kukurumidza kugadzirisa mushure mekurovedza muviri. Kana vanhu vachirovedzera muviri kana kurovedza muviri, muviri unoburitsa huwandu hwakawanda hweROS, iyo, kana isina kubviswa nenguva, inogona kukuvadza tsandanyama uye kukanganisa kupora kwemuviri, nepo astaxanthin's yakasimba antioxidant basa inogona kubvisa ROS munguva uye kugadzirisa yakakuvadzwa tsandanyama nekukurumidza.
Justgood Health inosuma yayo nyowani Astaxanthin Complex, yakawanda-musanganiswa we magnesium glycerophosphate, vhitamini B6 (pyridoxine), uye astaxanthin iyo inoderedza marwadzo emhasuru uye kuneta mushure mekurovedza muviri. Iyo fomula yakatarisana neJustgood Health's Whole Algae Complex, iyo inopa yakasikwa astaxanthin iyo isingango chengetedza tsandanyama kubva mukukuvadzwa kweoxidative, asi zvakare inosimudzira kuita kwemhasuru uye inovandudza kuita kwemumhanyi.
5) Utano hwemwoyo
Oxidative kusagadzikana uye kuzvimba kunoratidza pathophysiology yeatherosclerotic cardiovascular disease. Iyo yakanakisa antioxidant chiitiko cheastaxanthin inogona kudzivirira nekuvandudza atherosclerosis.
Justgood Health Triple Strength Natural Astaxanthin Softgels inobatsira kuchengetedza hutano hwemoyo nekushandisa yakasikwa astaxanthin inotorwa kubva muraraungu dzvuku algae, iyo mikuru yekumisikidza iyo inosanganisira astaxanthin, organic virgin kokonati mafuta uye yakasikwa tocopherols.
6) Immune Regulation
Immune system masero anonzwa zvakanyanya kune mahara radical kukuvara. Astaxanthin inochengetedza dziviriro ye immune system nekudzivirira mahara radical kukuvara. Chidzidzo chakawana kuti astaxanthin mumasero evanhu kuti abudise immunoglobulins, mumuviri womunhu astaxanthin supplementation kwemavhiki masere, astaxanthin mazinga muropa akawedzera, T masero uye B masero akawedzera, DNA kukuvara kwakaderedzwa, C-reactive protein yakaderedzwa zvakanyanya.
Astaxanthin softgels, mbishi astaxanthin, shandisa chiedza chezuva, mvura yakanatswa nelava uye simba rezuva kuburitsa yakachena uye ine hutano astaxanthin, inogona kubatsira kuwedzera kusadzivirirwa, kudzivirira kuona uye hutano hwakabatana.
7) Bvisa Kuneta
A 4-vhiki randomized, double-blind, placebo-controlled, two-way crossover study yakawana kuti astaxanthin yakakurudzira kupora kubva pakuona kwekuona terminal (VDT) -kukonzera kuneta kwepfungwa, kuderedza plasma yakakwira phosphatidylcholine hydroperoxide (PCOOH) mazinga panguva dzose dzepfungwa uye dzemuviri. Chikonzero chinogona kunge chiri che antioxidant chiitiko uye anti-kuzvimba nzira yeastaxanthin.
8) Kudzivirirwa kwechiropa
Astaxanthin ine inodzivirira uye inosimudzira mhedzisiro pamatambudziko ehutano senge chiropa fibrosis, chiropa ischemia-reperfusion kukuvara, uye NAFLD. Astaxanthin inogona kugadzirisa nzira dzakasiyana-siyana dzezviratidzo, zvakadai sokuderedza JNK uye ERK-1 basa rekuvandudza hepatic insulin resistance, inhibiting PPAR-γ kutaura kuderedza hepatic mafuta synthesis, uye pasi-inogadzirisa TGF-β1 / Smad3 kutaura kuti inhibit HSCs activation uye chiropa fibrosis.
Mamiriro emitemo munyika imwe neimwe
MuChina,astaxanthin kubva kunobva muraraungu dzvuku algae inogona kushandiswa sechinhu chitsva chekudya mukudya kwakawanda (kunze kwekudya kwevana), uyezve, United States, Canada neJapan zvakare inobvumira astaxanthin kushandiswa mukudya .
Nguva yekutumira: Zvita-05-2024